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KMID : 0942820030020020108
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Journal of Korean Brain Tumor Society
2003 Volume.2 No. 2 p.108 ~ p.114
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Concomitant Pituitary Adenoma and Rathke’s Cleft Cyst
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Kim Jeong-Hoon
Kwon Soon-Chan
Ahn Jae-Sung
Jeon Sang-Ryong
Ra Young-Shin
Kim Chang-Jin
Lee Jung-Kyo
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Abstract
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Objective: The goal of this study was to characterize the clinical, radiological, surgical, and pathological findings in patients with both pituitary adenoma and Rathke’s cleft cyst.
Methods: We conducted a retrospective study of patients with concomitant pituitary adenoma and Rathke’s cleft cyst operated on from 1991 through 2001 at our institution. Three patients were identified with this diagnosis. The medical
records, neuroradiologic studies, and histologies were reviewed.
Results: There were 771 patients with pituitary adenoma and 46 with Rathke’s cleft cyst in the same period. The frequency of the combination was 0.39 % of pituitary adenoma and 6.5% of Rathke’s cleft cyst. One case was associated
with hyperprolactinemia. Preoperative diagnosis on the basis of CT/MRI was pituitary adenoma in all three cases.
Transsphenoidal approaches were done for these three patients, and postoperative courses were uneventful. Hormonal and visual symptoms were improved. Histologically, the tumor was composed of typical pituitary adenoma and component compatible with Rathke’s cleft cyst.
Conclusion: When a non-enhancing cyst-like structure is demonstrated in a patient with pituitary adenoma, the possibility of a coexisting Rathke’s cleft cyst should be considered. Patients with this kind of pituitary tumor can be managed in the same fashion as patients with other types of pituitary adenoma.
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KEYWORD
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Pituitary adenoma, Rathke’s cleft cyst, Transsphenoidal approach
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